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Spectrin beta Chain, Erythrocyte (SPTB) anticorps

SPTB Reactivité: Humain, Souris, Rat WB, IF, IHC, Coat, ELISA, StM Hôte: Souris Monoclonal RG-26 unconjugated
N° du produit ABIN6940649
  • Antigène Voir toutes Spectrin beta Chain, Erythrocyte (SPTB) Anticorps
    Spectrin beta Chain, Erythrocyte (SPTB)
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 7
    • 4
    Souris
    Clonalité
    • 7
    • 4
    Monoclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Inconjugué
    Application
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Coating (Coat), ELISA, Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogène
    Red cell membranes
    Clone
    RG-26
    Isotype
    IgG2a kappa
  • Indications d'application

    Positive Control: Jurkat whole cell lysate (WB). Human colon carcinoma tissue (IHC).

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL), ,Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    Spectrin beta Chain, Erythrocyte (SPTB)
    Autre désignation
    SPTB (SPTB Produits)
    Synonymes
    anticorps AI842465, anticorps D330027P03Rik, anticorps Gm1301, anticorps Spnb-1, anticorps Spnb1, anticorps ja, anticorps jaundiced, anticorps mKIAA4219, anticorps EL3, anticorps HS2, anticorps HSPTB1, anticorps SPH2, anticorps spectrin beta, erythrocytic, anticorps spectrin, beta, erythrocytic, anticorps SPTB, anticorps Sptb
    Sujet
    Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded, usually leading to cell death.
    Poids moléculaire
    246kDa
    ID gène
    6710
    UniProt
    O15020
    Pathways
    Regulation of Actin Filament Polymerization
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