TIMP3 anticorps (AA 175-211)

N° du produit ABIN6940740

Détail du produit anti-TIMP3 anticorps

Antigène: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Épitope: AA 175-211

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMP3 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)

Immunogène: The amino acid sequence (aa175-211), used as the immunogen for TIMP3 Ab, is 100% homologous in human, cow, dog and horse, and 94% homologous in Mouse and rat.

Isotype: IgG

Information d'application

Indications d'application:

Positive Control: Placenta or breast carcinoma.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur TIMP3

Antigène: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Autre désignation: TIMP3 (TIMP3 Produits)

Synonymes: anticorps TIMP-3, anticorps TIMP3, anticorps timp3, anticorps HSMRK222, anticorps K222, anticorps K222TA2, anticorps SFD, anticorps IMP-3, anticorps timp3-A, anticorps Timp-3, anticorps metalloproteinase inhibitor 3, anticorps TIMP metallopeptidase inhibitor 3, anticorps Metalloproteinase inhibitor 3, anticorps TIMP metallopeptidase inhibitor 3 L homeolog, anticorps tissue inhibitor of metalloproteinase 3, anticorps CpipJ_CPIJ003282, anticorps TIMP3, anticorps timp3, anticorps Timp3, anticorps timp3.L

Sujet: TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP's inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

Poids moléculaire: 30kDa

ID gène: 7078

UniProt: P35625