Recombinant GRP94 anticorps

N° du produit ABIN6940801

Détail du produit anti-GRP94 anticorps

Antigène: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet, Hamster, Chien, Lapin, Porc, Cobaye, Singe, Mouton, Cheval, Xenopus laevis

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GRP94 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)

Specificité: Recognizes a protein of 94 kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp's are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human HSP90B1 protein

Clone: HSP90B1-3168R

Isotype: IgG

Information d'application

Indications d'application:

Positive Control: HepG2, U20S cells. About 50 % of breast tumors express grp94 protein.

Known Application: Flow Cytometry (0.5-1 μg/million cells),Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur GRP94

Antigène: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Autre désignation: HSP90B1 (HSP90B1 Produits)

Synonymes: anticorps ecgp, anticorps gp96, anticorps tra1, anticorps grp94, anticorps DDBDRAFT_0206450, anticorps DDBDRAFT_0215015, anticorps DDB_0206450, anticorps DDB_0215015, anticorps TRA1, anticorps HSP90B1, anticorps ERp99, anticorps GRP94, anticorps TA-3, anticorps Targ2, anticorps Tra-1, anticorps Tra1, anticorps endoplasmin, anticorps GP96, anticorps fb61d09, anticorps tra-1, anticorps wu:fb61d09, anticorps wu:fq25g01, anticorps Grp94, anticorps ECGP, anticorps Gp96, anticorps ppk98, anticorps hsp108, anticorps heat shock protein 90kDa beta (Grp94), member 1, anticorps heat shock protein Hsp90 family protein, anticorps 94 kD glucose-regulated protein, anticorps heat shock protein 90 beta family member 1, anticorps heat shock protein 90, beta (Grp94), member 1, anticorps heat shock protein 90, beta (grp94), member 1, anticorps heat shock protein 90kDa beta family member 1 L homeolog, anticorps hsp90b1, anticorps grp94, anticorps HSP90B1, anticorps Hsp90b1, anticorps hsp90b1.L

Poids moléculaire: 94kDa

ID gène: 7184

UniProt: P14625

Pathways: Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades