Recombinant GRP94 anticorps
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- Antigène Voir toutes GRP94 (HSP90B1) Anticorps
- GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
- Type d'anticorp
- Recombinant Antibody
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Poulet, Hamster, Chien, Lapin, Porc, Cobaye, Singe, Mouton, Cheval, Xenopus laevis
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GRP94 est non-conjugé
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Application
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)
- Specificité
- Recognizes a protein of 94 kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp's are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant full-length human HSP90B1 protein
- Clone
- HSP90B1-3168R
- Isotype
- IgG
- Top Product
- Discover our top product HSP90B1 Anticorps primaire
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- Indications d'application
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Positive Control: HepG2, U20S cells. About 50 % of breast tumors express grp94 protein.
Known Application: Flow Cytometry (0.5-1 μg/million cells),Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
- Autre désignation
- HSP90B1 (HSP90B1 Produits)
- Poids moléculaire
- 94kDa
- ID gène
- 7184
- UniProt
- P14625
- Pathways
- Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades
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