VCAM1 anticorps
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- Antigène Voir toutes VCAM1 Anticorps
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp VCAM1 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
- Specificité
- Recognizes a protein of 110 kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
- Purification
- Purified by Protein A/G
- Immunogène
- Stimulated human umbilical vein endothelial cells (HUVEC)
- Clone
- 1-4C3
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product VCAM1 Anticorps primaire
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- Indications d'application
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Positive Control: Human placenta or tonsil.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
- Autre désignation
- VCAM1 (VCAM1 Produits)
- Synonymes
- anticorps CD106, anticorps INCAM-100, anticorps Vcam-1, anticorps VCAM1B, anticorps fi76d06, anticorps wu:fi76d06, anticorps zgc:158875, anticorps VCAM1, anticorps vascular cell adhesion molecule 1, anticorps vascular cell adhesion molecule 1b, anticorps VCAM1, anticorps Vcam1, anticorps vcam1b, anticorps VCAM-1
- Poids moléculaire
- 110kDa
- ID gène
- 7412
- UniProt
- P19320
- Pathways
- Carbohydrate Homeostasis
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