VTCN1 anticorps

N° du produit ABIN6940936

Détail du produit anti-VTCN1 anticorps

Antigène: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VTCN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogène: A recombinant fragment of human B7-H4 protein (exact sequence is proprietary)

Clone: B7H4-1788

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Positive Control: HCT116, HeLa, SKBr-3, MCF-7 cells. Ovary, Pancreas, Placenta or Spleen.

Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Flow Cytometry (1-2 μg/million cells in 0.1ml), ,Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur VTCN1

Antigène: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Autre désignation: VTCN1 (VTCN1 Produits)

Synonymes: anticorps B7h4, anticorps B7s1, anticorps B7x, anticorps BC032925, anticorps B7-H4, anticorps B7H4, anticorps B7S1, anticorps B7X, anticorps B7h.5, anticorps PRO1291, anticorps VCTN1, anticorps RGD1311204, anticorps V set domain containing T cell activation inhibitor 1 L homeolog, anticorps V-set domain containing T cell activation inhibitor 1, anticorps V-set domain containing T-cell activation inhibitor 1, anticorps V set domain containing T cell activation inhibitor 1, anticorps vtcn1.L, anticorps VTCN1, anticorps vtcn1, anticorps Vtcn1

Sujet: T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer.

Poids moléculaire: 35kDa

ID gène: 79679

UniProt: Q7Z7D3