Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CAPNL1 anticorps

CAPNL1 Reactivité: Humain ELISA, IHC, Coat, StM Hôte: Souris Monoclonal CAPN1-1530 unconjugated
N° du produit ABIN6940954
  • Antigène Voir toutes CAPNL1 Anticorps
    CAPNL1 (Calpain 1, Large Subunit (CAPNL1))
    Reactivité
    • 50
    • 18
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 46
    • 10
    • 1
    Souris
    Clonalité
    • 49
    • 8
    Monoclonal
    Conjugué
    • 34
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp CAPNL1 est non-conjugé
    Application
    • 33
    • 21
    • 18
    • 9
    • 8
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Coating (Coat), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant full-length human CAPN1 protein
    Clone
    CAPN1-1530
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CAPNL1 Anticorps primaire
  • Indications d'application

    Positive Control: HeLa cells. Skin or Tonsil.

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CAPNL1 (Calpain 1, Large Subunit (CAPNL1))
    Autre désignation
    CAPN1 (CAPNL1 Produits)
    Synonymes
    anticorps CANP, anticorps CANP1, anticorps CANPL1, anticorps muCANP, anticorps muCL, anticorps Capa-1, anticorps Capa1, anticorps mu-calpin, anticorps si:ch211-203k12.4, anticorps si:dkeyp-101g1.3, anticorps calpain, anticorps calpain 1, anticorps calpain 1, (mu/I) large subunit, anticorps calpain 1, (mu/I) large subunit b, anticorps calpain 11, anticorps CAPN1, anticorps Capn1, anticorps capn1, anticorps capn1b, anticorps CAPN11
    Sujet
    Calpain 1 is an intracellular calcium-dependent protease that cleaves cytoskeletal and sub-membranous proteins. Calpains are non-lysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2+- dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit and one of three large catalytic subunits, designated Calpain 1, Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpain 1 co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction.
    Poids moléculaire
    80kDa
    ID gène
    823
    UniProt
    P07384
    Pathways
    Apoptose
Vous êtes ici:
Support technique