CD1c anticorps

N° du produit ABIN6941008

Détail du produit anti-CD1c anticorps

Antigène: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD1c est non-conjugé

Application: ELISA, Coating (Coat)

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human CD1c protein

Clone: CD1C-1603

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Expressed on cortical thymocytes, on certain T-cell leukemias and in various other tissues.

Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD1c

Antigène: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Autre désignation: CD1C (CD1C Produits)

Synonymes: anticorps BDCA1, anticorps CD1, anticorps CD1A, anticorps R7, anticorps CD1c molecule, anticorps CD1C

Sujet: The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with -2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1

Poids moléculaire: 43kDa

ID gène: 911

UniProt: P29017