RCAS1 anticorps
-
- Antigène Voir toutes RCAS1 (EBAG9) Anticorps
- RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp RCAS1 est non-conjugé
-
Application
- Immunohistochemistry (IHC), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant full-length human EBAG9 protein
- Clone
- CPTC-EBAG9-2
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product EBAG9 Anticorps primaire
-
-
- Indications d'application
-
Positive Control: MCF-7, Jurkat, 293 cell lysates, Human skeletal muscle tissue.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
-
- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
-
- Antigène
- RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))
- Autre désignation
- EBAG9 (EBAG9 Produits)
- Synonymes
- anticorps EB9, anticorps PDAF, anticorps MGC56608, anticorps zgc:56608, anticorps MGC84425, anticorps EBAG9, anticorps AI835379, anticorps Rcas1, anticorps RCAS1, anticorps eb9, anticorps pdaf, anticorps rcas1, anticorps estrogen receptor binding site associated, antigen, 9, anticorps estrogen receptor binding site associated, antigen, 9 L homeolog, anticorps estrogen receptor-binding fragment-associated gene 9, anticorps EBAG9, anticorps ebag9, anticorps ebag9.L, anticorps Ebag9
- Sujet
- EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
- Poids moléculaire
- 32kDa
- ID gène
- 9166
- UniProt
- O00559
-