CD3 epsilon anticorps (AA 23-119)
-
- Antigène Voir toutes CD3 epsilon (CD3E) Anticorps
- CD3 epsilon (CD3E)
-
Épitope
- AA 23-119
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp CD3 epsilon est non-conjugé
-
Application
- Flow Cytometry (FACS), Western Blotting (WB)
- Specificité
- Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant human CD3e fragment (aa 23-119)
- Clone
- C3e-1308
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product CD3E Anticorps primaire
-
-
- Indications d'application
-
Positive Control: Jurkat cells. Tonsil and lymph node.
Known Application: Western Blot (1-2 μg/mL for 60 minutes at RT),Flow Cytometry (1-2 μg/million cells),Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
-
- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
-
- Antigène
- CD3 epsilon (CD3E)
- Autre désignation
- CD3E (CD3E Produits)
- Poids moléculaire
- 20kDa
- ID gène
- 916
- UniProt
- P07766
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
-