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CD3 epsilon anticorps (AA 23-119)

CD3E Reactivité: Humain FACS, WB Hôte: Souris Monoclonal C3e-1308 unconjugated
N° du produit ABIN6941033
  • Antigène Voir toutes CD3 epsilon (CD3E) Anticorps
    CD3 epsilon (CD3E)
    Épitope
    • 24
    • 19
    • 16
    • 16
    • 12
    • 10
    • 9
    • 8
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-119
    Reactivité
    • 230
    • 176
    • 51
    • 42
    • 18
    • 8
    • 8
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 139
    • 124
    • 46
    • 23
    • 23
    • 10
    • 1
    • 1
    • 1
    Souris
    Clonalité
    • 249
    • 112
    • 7
    Monoclonal
    Conjugué
    • 143
    • 33
    • 29
    • 21
    • 18
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD3 epsilon est non-conjugé
    Application
    • 268
    • 148
    • 107
    • 86
    • 84
    • 69
    • 31
    • 27
    • 25
    • 22
    • 14
    • 13
    • 13
    • 13
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB)
    Specificité
    Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant human CD3e fragment (aa 23-119)
    Clone
    C3e-1308
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product CD3E Anticorps primaire
  • Indications d'application

    Positive Control: Jurkat cells. Tonsil and lymph node.

    Known Application: Western Blot (1-2 μg/mL for 60 minutes at RT),Flow Cytometry (1-2 μg/million cells),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CD3 epsilon (CD3E)
    Autre désignation
    CD3E (CD3E Produits)
    Poids moléculaire
    20kDa
    ID gène
    916
    UniProt
    P07766
    Pathways
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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