Aurora Kinase B anticorps (AA 89-251)
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- Antigène Voir toutes Aurora Kinase B (AURKB) Anticorps
- Aurora Kinase B (AURKB)
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Épitope
- AA 89-251
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Aurora Kinase B est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- Recognizes a protein of 39 kDa, which is identified as Aurora B. The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant fragment (around aa 89-251) of human Aurora B protein (exact sequence is proprietary)
- Clone
- AURKB-1521
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product AURKB Anticorps primaire
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anti-Aurora Kinase B (AURKB) (AA 223-234), (pThr232) antibody
AURKB Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Aurora Kinase B (AURKB) (AA 1-90) antibodyAURKB Reactivité: Humain WB, ELISA, IF, IP Hôte: Souris Monoclonal 6H7 unconjugated
anti-Aurora Kinase B (AURKB) (AA 6-35) antibodyAURKB Reactivité: Humain, Souris, Rat, Primate WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Aurora Kinase B (AURKB) antibodyAURKB Reactivité: Humain WB, ELISA, IHC, IP Hôte: Lapin Monoclonal 4E5 unconjugated Recombinant Antibody
anti-Aurora Kinase B (AURKB) (AA 1-90) antibodyAURKB Reactivité: Humain WB, ELISA, RNAi Hôte: Souris Monoclonal 6G8 unconjugated
anti-Aurora Kinase B (AURKB) (AA 89-251) antibodyAURKB Reactivité: Humain IHC, StM Hôte: Souris Monoclonal rAURKB-1592 unconjugated Recombinant Antibody
anti-Aurora Kinase B (AURKB) (pThr232) antibodyAURKB Reactivité: Humain, Souris, Rat, Singe WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Aurora Kinase B (AURKB) (AA 1-255) antibodyAURKB Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Aurora Kinase B (AURKB) (AA 89-251) antibodyAURKB Reactivité: Humain IHC, StM Hôte: Souris Monoclonal AURKB-1592 unconjugated
anti-Aurora Kinase B (AURKB) (pThr232) antibodyAURKB Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache) WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
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Positive Control: HeLa cells. Tonsil, Placenta, Hodgkin's Lymphoma or Colon Carcinoma.
Known Application: Western Blot (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- Aurora Kinase B (AURKB)
- Autre désignation
- AURKB (AURKB Produits)
- Poids moléculaire
- 39kDa
- ID gène
- 9212
- UniProt
- Q96GD4
- Pathways
- TCR Signaling, Cycle Cellulaire, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
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