Recombinant CD8 alpha anticorps
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- Antigène Voir toutes CD8 alpha (CD8A) Anticorps
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Type d'anticorp
- Recombinant Antibody
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD8 alpha est non-conjugé
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Application
- Immunohistochemistry (IHC), ELISA, Staining Methods (StM), Coating (Coat)
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant full-length human CD8A protein
- Clone
- RC8-468
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD8A Anticorps primaire
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- Indications d'application
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Positive Control: HuT78 or hPBL. Tonsil.
Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Autre désignation
- CD8A (CD8A Produits)
- Sujet
- CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
- Poids moléculaire
- 32kDa
- ID gène
- 925
- UniProt
- P01732
- Pathways
- TCR Signaling
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