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Recombinant CD20 anticorps

MS4A1 Reactivité: Humain FACS, IHC, IF, StM Hôte: Souris Monoclonal rIGEL-773 unconjugated Recombinant Antibody
N° du produit ABIN6941111
  • Antigène Voir toutes CD20 (MS4A1) Anticorps
    CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 270
    • 63
    • 28
    • 20
    • 19
    • 18
    • 11
    • 7
    • 6
    • 4
    • 2
    • 1
    Humain
    Hôte
    • 199
    • 98
    • 4
    • 2
    Souris
    Clonalité
    • 218
    • 83
    • 1
    Monoclonal
    Conjugué
    • 110
    • 21
    • 19
    • 18
    • 14
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    Cet anticorp CD20 est non-conjugé
    Application
    • 214
    • 92
    • 78
    • 52
    • 48
    • 33
    • 25
    • 20
    • 17
    • 16
    • 14
    • 13
    • 11
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
    Specificité
    Recognizes a protein of 30-33 kDa, which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre-B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant full-length human MS4A1 fragment
    Clone
    RIGEL-773
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product MS4A1 Anticorps primaire
  • Indications d'application

    Positive Control: Daudi, Raji or U266 (FACS). Human lymphocytes. Lymph node and tonsil (IHC).

    Known Application: Immunofluorescence (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), ,Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
    Autre désignation
    MS4A1 (MS4A1 Produits)
    Synonymes
    anticorps B1, anticorps Bp35, anticorps CD20, anticorps CVID5, anticorps LEU-16, anticorps MS4A2, anticorps S7, anticorps AA960661, anticorps Cd20, anticorps Ly-44, anticorps Ms4a2, anticorps MS4A1, anticorps bp35, anticorps cd20, anticorps ms4a2, anticorps leu-16, anticorps ms4a4c, anticorps cd20-like, anticorps membrane spanning 4-domains A1, anticorps membrane-spanning 4-domains, subfamily A, member 1, anticorps B-lymphocyte antigen CD20, anticorps MS4A1, anticorps Ms4a1, anticorps ms4a1, anticorps LOC101694281
    Poids moléculaire
    33-37kDa
    ID gène
    931
    UniProt
    P11836
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