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CD22 anticorps

CD22 Reactivité: Humain, Souris, Rat FACS, IM Hôte: Souris Monoclonal MYG13 unconjugated
N° du produit ABIN6941118
  • Antigène Voir toutes CD22 Anticorps
    CD22 (CD22 Molecule (CD22))
    Reactivité
    • 143
    • 51
    • 23
    • 5
    • 3
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 90
    • 62
    • 16
    Souris
    Clonalité
    • 115
    • 55
    Monoclonal
    Conjugué
    • 83
    • 15
    • 13
    • 11
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD22 est non-conjugé
    Application
    • 102
    • 74
    • 45
    • 38
    • 36
    • 20
    • 13
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunomicroscopy (IM)
    Specificité
    Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
    Purification
    Purified by Protein A/G
    Immunogène
    Human Raji cells
    Clone
    MYG13
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD22 Anticorps primaire
  • Indications d'application

    Positive Control: Ramos, Raji, Daudi, IM9, JY25 and human peripheral blood lymphocytes. Human tonsil and lymphocytes.

    Known Application: Flow Cytometry (0.5-1 μg/million cells),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CD22 (CD22 Molecule (CD22))
    Autre désignation
    CD22 (CD22 Produits)
    Synonymes
    anticorps A530093D23, anticorps Lyb-8, anticorps Lyb8, anticorps SIGLEC-2, anticorps SIGLEC2, anticorps siglec-2, anticorps CD22 antigen, anticorps CD22 molecule, anticorps Cd22, anticorps CD22
    Poids moléculaire
    130-140kDa
    ID gène
    933
    UniProt
    P20273
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