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CD79a anticorps

CD79A Reactivité: Humain FACS, IF, WB, IHC, ELISA, StM, Coat Hôte: Souris Monoclonal ZL7-4 unconjugated
N° du produit ABIN6941261
  • Antigène Voir toutes CD79a (CD79A) Anticorps
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    Reactivité
    • 184
    • 99
    • 79
    • 51
    • 50
    • 32
    • 27
    • 25
    • 25
    • 25
    • 15
    • 10
    • 5
    • 4
    • 2
    • 1
    Humain
    Hôte
    • 100
    • 96
    • 3
    • 1
    Souris
    Clonalité
    • 119
    • 80
    • 1
    Monoclonal
    Conjugué
    • 89
    • 18
    • 15
    • 14
    • 14
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD79a est non-conjugé
    Application
    • 113
    • 90
    • 60
    • 56
    • 47
    • 22
    • 20
    • 13
    • 9
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Staining Methods (StM), Coating (Coat)
    Purification
    Purified by Protein A/G
    Immunogène
    IgM complex isolated from Daudi cells.
    Clone
    ZL7-4
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD79A Anticorps primaire
  • Indications d'application

    Positive Control: Raji, Daudi, Ramos cells. Germinal center B- cells in a lymph node or tonsil.

    Known Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1.0 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    Autre désignation
    CD79A (CD79A Produits)
    Synonymes
    anticorps CD79A, anticorps Ig-alpha, anticorps Iga, anticorps Igalpha, anticorps Ly-54, anticorps Ly54, anticorps mb-1, anticorps IGA, anticorps MB-1, anticorps IG-alpha, anticorps CD79a molecule, anticorps CD79A antigen (immunoglobulin-associated alpha), anticorps Cd79a molecule-like, anticorps CD79A, anticorps Cd79a, anticorps Cd79al
    Sujet
    A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.
    Poids moléculaire
    44kDa
    ID gène
    973
    UniProt
    P11912
    Pathways
    BCR Signaling
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