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CA 19-9 anticorps

CA 19-9 Reactivité: Humain IHC, StM Hôte: Lapin Monoclonal CA19-9-1390R unconjugated
N° du produit ABIN6941454
  • Antigène Voir toutes CA 19-9 Anticorps
    CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))
    Reactivité
    • 35
    • 1
    • 1
    Humain
    Hôte
    • 23
    • 14
    Lapin
    Clonalité
    • 33
    • 3
    Monoclonal
    Conjugué
    • 20
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CA 19-9 est non-conjugé
    Application
    • 19
    • 15
    • 15
    • 14
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificité
    CA19-9, a carbohydrate epitope expressed on a high MW (400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.
    Immunogène
    Purified human CA19-9 protein
    Clone
    CA19-9-1390R
    Isotype
    IgG
    Top Product
    Discover our top product CA 19-9 Anticorps primaire
  • Indications d'application

    Positive Control: Stomach or Colon Carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (5-10 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))
    Autre désignation
    CA19-9/Sialyl Lewisa (GI Tumor Marker) (CA 19-9 Produits)
    Poids moléculaire
    >400kDa
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