CBX7 anticorps
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- Antigène Voir toutes CBX7 Anticorps
- CBX7 (Chromobox Homolog 7 (CBX7))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CBX7 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Réactivité croisée
- Humain
- Purification
- Purified by Protein A.
- Immunogène
- Recombinant protein within human cbx7 aa 1-150
- Clone
- 5C5
- Isotype
- IgG
- Top Product
- Discover our top product CBX7 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
FCM 1:20-100 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CBX7 (Chromobox Homolog 7 (CBX7))
- Autre désignation
- CBX7 (CBX7 Produits)
- Synonymes
- anticorps 1600014J01Rik, anticorps AI851678, anticorps D15Ertd417e, anticorps zgc:110152, anticorps chromobox 7, anticorps chromobox homolog 7a, anticorps CBX7, anticorps Cbx7, anticorps cbx7a
- Sujet
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Synonyms: Chromobox protein homolog 7, CBX7.
Background: CBX7 (Chromobox protein homolog 7) is a 251 amino acid nuclear protein that contains one N-terminal chromodomain and one C-terminal Pc box. Highly expressed in kidney, brain, heart and skeletal muscle, with weaker expression in peripheral blood leukocytes, CBX7 functions as a component of the chromatin-associated polycomb complex (PcG) and is involved in maintaining the transcriptionally repressed state of target genes. Additionally, CBX7 modifies chromatin and is thought to extend the cellular life span of epithelial cells by repressing p14 ARF expression, while simultaneously repressing telomerase activity. Due to its ability to repress the transcription of cell-cycle-related proteins, CBX7 is thought to play a role in tumorigenesis, specifically in the development of follicular lymphoma and thyroid cancer.
- ID gène
- 23492
- UniProt
- O95931
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