Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CMA1 anticorps

CMA1 Reactivité: Humain, Rat WB, IHC (p) Hôte: Lapin Monoclonal 1G11 unconjugated
N° du produit ABIN6942587
  • Antigène Voir toutes CMA1 Anticorps
    CMA1 (Chymase 1, Mast Cell (CMA1))
    Reactivité
    • 32
    • 21
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 41
    • 9
    • 1
    • 1
    Lapin
    Clonalité
    • 36
    • 16
    Monoclonal
    Conjugué
    • 26
    • 9
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CMA1 est non-conjugé
    Application
    • 29
    • 21
    • 18
    • 9
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Rat
    Purification
    Purified by Protein A.
    Immunogène
    Recombinant protein within human Mast Cell Chymase aa 50-200
    Clone
    1G11
    Isotype
    IgG
    Top Product
    Discover our top product CMA1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CMA1 (Chymase 1, Mast Cell (CMA1))
    Autre désignation
    CMA1 (CMA1 Produits)
    Synonymes
    anticorps CYH, anticorps MCT1, anticorps chymase, anticorps MMCP-5, anticorps Mcp-5, anticorps Mcp5, anticorps Mcpt5, anticorps MCP3P, anticorps CMA1, anticorps Chymase, anticorps chymase 1, anticorps chymase 1, mast cell, anticorps chymase-like, anticorps CMA1, anticorps Cma1, anticorps LOC100008644
    Sujet

    Synonyms: Chymase 1, Alpha-chymase, Mast cell protease I, CMA1, CYH, CYM.

    Background: Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Mast Cell Chymase, also known as CMA1 or MCT1, is a major secreted serine protease that is involved in vasoactive peptide generation, extracellular matrix degradation and regulation of gland secretion. The human chymase gene, which maps to human chromosome 14q11.2, encodes a preproenzyme with a 19 amino acid signal peptide, an acidic 2 amino acid propeptide and a 226 amino acid catalytic domain. Mast Cell Chymase is a chymotryptic serine proteinase which is a member of the peptidase family S1. Expressed in mast cells, Mast Cell Chymase is associated with the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. Mast cell proteases are a family of rodent protein homologs to human tryptases that are specifically expressed in mast cells and may serve as highly specific markers in the analysis of mast cell heterogeneity, differentiation and function.

    ID gène
    1215
    UniProt
    P23946
    Pathways
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
Vous êtes ici:
Support technique