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CTU2 anticorps (AA 301-400) (AbBy Fluor® 555)

CTU2 Reactivité: Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 555
N° du produit ABIN6942726
  • Antigène Voir toutes CTU2 Anticorps
    CTU2 (Cytosolic Thiouridylase Subunit 2 (CTU2))
    Épitope
    • 14
    • 1
    AA 301-400
    Reactivité
    • 15
    • 3
    Souris
    Hôte
    • 17
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CTU2 est conjugé à/à la AbBy Fluor® 555
    Application
    • 17
    • 12
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CTU2/C16orf84
    Isotype
    IgG
    Top Product
    Discover our top product CTU2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CTU2 (Cytosolic Thiouridylase Subunit 2 (CTU2))
    Autre désignation
    CTU2 (CTU2 Produits)
    Synonymes
    anticorps C16orf84, anticorps NCS2, anticorps UPF0432, anticorps Ncs2, anticorps 2310061F22Rik, anticorps cytosolic thiouridylase subunit 2, anticorps CTU2, anticorps Ctu2
    Sujet

    Synonyms: C16orf84, ctu2, CTU2_HUMAN, Cytoplasmic tRNA 2-thiolation protein 2, cytosolic thiouridylase subunit 2 homolog (S. pombe), NCS2, PF0432.

    Background: CTU2 is a 515 amino acid cytoplasmic protein that plays a role in the 2-thiolation of mcm(5)S(2)U at wobble positions of tRNA. CTU2 forms a complex with CTU1 and Urm1, and may also form a separate heterodimer with CTU1 to ligate sulfur from thiocarboxylated Urm1 onto tRNA. Existing as three alternatively spliced isoforms, the gene encoding CTU2 maps to human chromosome 16q24.3. Chromosome 16 encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

    ID gène
    348180
    UniProt
    Q2VPK5
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