DDX6 anticorps
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- Antigène Voir toutes DDX6 Anticorps
- DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DDX6 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- Recombinant protein within human DDX6 aa 100-300
- Clone
- 15C2
- Isotype
- IgG
- Top Product
- Discover our top product DDX6 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))
- Autre désignation
- DDX6 (DDX6 Produits)
- Synonymes
- anticorps si:ch211-147p17.1, anticorps P54H, anticorps Xp54, anticorps hlr2, anticorps me31b, anticorps p54, anticorps rck, anticorps HLR2, anticorps P54, anticorps RCK, anticorps p54h, anticorps RGD1564560, anticorps 1110001P04Rik, anticorps E230023J21Rik, anticorps mRCK/P54, anticorps DEAD-box helicase 6, anticorps DEAD (Asp-Glu-Ala-Asp) box helicase 6, anticorps DEAD-box helicase 6 L homeolog, anticorps DEAD (Asp-Glu-Ala-Asp) box polypeptide 6, anticorps DDX6, anticorps ddx6, anticorps ddx6.L, anticorps Ddx6
- Sujet
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Synonyms: Probable ATP-dependent RNA helicase DDX6, ATP-dependent RNA helicase p54, DEAD box protein 6, Oncogene RCK, DDX6, HLR2, RCK.
Background: RCK, also known as DDX6 and P54, is a member of the DEAD-box RNA helicase family of proteins, all of which share common protein motifs. Found in most tissues, RCK is an unwindase that exhibits ATP-dependent RNA un-winding activity, as well as the ability to decay RNA in the 5'-3' direction. In non-malignant cells, RCK is associated with all processes of normal RNA metabolism including splicing, export and translation initiation. Mutations in the gene encoding RCK can cause the protein to be overexpressed, changing its function to that of an oncogene that positively regulates the expression of genes involved in cell growth and proliferation. It is believed that, through its unwindase activity, the main function of RCK is to downregulate mRNA expression and maintain normal transcriptional levels within the cell.
- ID gène
- 1656
- UniProt
- P26196
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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