DENND1A anticorps (AA 42-140) (Biotin)

N° du produit ABIN6942845

Détail du produit anti-DENND1A anticorps (Biotin)

Antigène: DENND1A (DENN/MADD Domain Containing 1A (DENND1A))

Épitope: AA 42-140

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DENND1A est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DENND1A

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur DENND1A

Antigène: DENND1A (DENN/MADD Domain Containing 1A (DENND1A))

Autre désignation: DENND1A (DENND1A Produits)

Synonymes: anticorps RGD1307927, anticorps FAM31A, anticorps KIAA1608, anticorps RP11-230L22.3, anticorps 6030446I19Rik, anticorps connecdenn, anticorps fam31a, anticorps DENN domain containing 1A, anticorps DENN/MADD domain containing 1A, anticorps DENN domain-containing protein 1A, anticorps DENN domain containing 1A S homeolog, anticorps Dennd1a, anticorps DENND1A, anticorps dennd1a, anticorps LOC100512328, anticorps dennd1a.S

Sujet:

Synonyms: Connecdenn 1, Connecdenn, DEN1A_HUMAN, DENN domain-containing protein 1A, DENN/MADD domain containing 1A, dennd1a, FAM31A, FLJ21129, FLJ38464, KIAA1608, OTTHUMP00000022090, Protein FAM31A, RP11 230L22.3.

Background: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]

ID gène: 57706

UniProt: Q8TEH3