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DEPTOR anticorps (AA 151-250) (Biotin)

DEPTOR Reactivité: Humain, Souris WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN6942875
  • Antigène Voir toutes DEPTOR Anticorps
    DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
    Épitope
    • 15
    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reactivité
    • 51
    • 33
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris
    Hôte
    • 46
    • 4
    • 1
    Lapin
    Clonalité
    • 49
    • 2
    Polyclonal
    Conjugué
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DEPTOR est conjugé à/à la Biotin
    Application
    • 43
    • 26
    • 26
    • 9
    • 7
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DEPTOR
    Isotype
    IgG
    Top Product
    Discover our top product DEPTOR Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
    Autre désignation
    DEPTOR (DEPTOR Produits)
    Synonymes
    anticorps DEP.6, anticorps DEPDC6, anticorps 4731402B04Rik, anticorps 9130412E02Rik, anticorps D15Ertd336e, anticorps D15Ertd597e, anticorps Depdc6, anticorps Depdc6-001, anticorps Depdc6-002, anticorps R75183, anticorps mKIAA4200, anticorps RGD1561030, anticorps RAPGEF4, anticorps DEP domain containing MTOR interacting protein, anticorps DEP domain containing MTOR-interacting protein, anticorps DEPTOR, anticorps Deptor
    Sujet

    Synonyms: DEP domain containing 6, DEP domain-containing mTOR-interacting protein, DEP domain-containing protein 6, DEPDC6, DEPTOR, DPTOR_HUMAN.

    Background: DEPTOR (DEP domain containing MTOR-interacting protein), also known as DEP.6 or DEPDC6 (DEP domain-containing protein 6), is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways. DEPTOR interacts with FRAP via its PDZ domain, and undergoes post-translational phosphorylation. Containing two DEP domains and one PDZ (DHR) domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24.12. Chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

    ID gène
    64798
    UniProt
    Q8TB45
    Pathways
    Signalisation PI3K-Akt, Signalisation RTK, Regulation of Cell Size, BCR Signaling, L'effet Warburg
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