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DUSP26 anticorps (AA 111-211) (Biotin)

DUSP26 Reactivité: Rat ELISA, WB, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN6943139
  • Antigène Voir toutes DUSP26 Anticorps
    DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))
    Épitope
    • 15
    • 14
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 111-211
    Reactivité
    • 35
    • 31
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Rat
    Hôte
    • 58
    • 1
    Lapin
    Clonalité
    • 60
    Polyclonal
    Conjugué
    • 18
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DUSP26 est conjugé à/à la Biotin
    Application
    • 39
    • 26
    • 26
    • 15
    • 11
    • 9
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DUSP26
    Isotype
    IgG
    Top Product
    Discover our top product DUSP26 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))
    Autre désignation
    DUSP26 (DUSP26 Produits)
    Synonymes
    anticorps DUSP24, anticorps LDP-4, anticorps MKP8, anticorps NATA1, anticorps SKRP3, anticorps 2310043K02Rik, anticorps Skrp3, anticorps RGD1310090, anticorps dual specificity phosphatase 26, anticorps dual specificity phosphatase 26 (putative), anticorps DUSP26, anticorps Dusp26
    Sujet

    Synonyms: DSP-4, Dual specificity phosphatase 26 (putative), Dual specificity phosphatase 26, Dual specificity phosphatase SKRP3, Dual specificity protein phosphatase 26, DUS26_HUMAN, DUSP24, DUSP26, Hypothetical protein FLJ31142, LDP 4, LDP-4, Low molecular mass dual specificity phosphatase 4, Low-molecular-mass dual-specificity phosphatase 4, MAP kinase phosphatase 8, MGC1136, MGC2627, Mitogen activated protein kinase phosphatase 8, Mitogen-activated protein kinase phosphatase 8, MKP-8, MKP8, NATA1, NATA1 protein, Novel amplified gene in thyroid anaplastic cancer, SKRP3.

    Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways, which are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DUSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DUSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP26, also designated LDP4, MKP8, NATA1 and SKRP3, is ubiquitously expressed in brain except in the hippocampus. DUSP26 dephosphorylates p38 thereby inhibiting p38-mediated apoptosis in anaplastic thyroid cancer cells. Downregulation of DUSP26 may also contribute to malignant phenotypes of glioma.

    ID gène
    78986
    UniProt
    Q9BV47
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