EFR3B anticorps (AA 21-120) (Biotin)

N° du produit ABIN6943216

Détail du produit anti-EFR3B anticorps (Biotin)

Antigène: EFR3B (EFR3 Homolog B (EFR3B))

Épitope: AA 21-120

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EFR3B est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EFR3B

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur EFR3B

Antigène: EFR3B (EFR3 Homolog B (EFR3B))

Autre désignation: EFR3B (EFR3B Produits)

Synonymes: anticorps KIAA0953, anticorps AI852640, anticorps C030014M07Rik, anticorps mKIAA0953, anticorps efr3b, anticorps si:ch211-203k16.1, anticorps si:ch211-215m21.18, anticorps si:dkeyp-70e6.6, anticorps EFR3 homolog B, anticorps EFR3 homolog Bb (S. cerevisiae), anticorps EFR3B, anticorps Efr3b, anticorps efr3bb

Sujet:

Synonyms: EFR3B, EFR3B_HUMAN, KIAA0953, Protein EFR3 homolog B.

Background: EFR3B (EFR3 homolog B) is an 817 amino acid protein that exists as three alternatively spliced isoforms and belongs to the EFR3 family. The gene encoding EFR3B maps to human chromosome 2p23.3 and mouse chromosome 12 A1.1. Human chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr_ syndrome, is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

ID gène: 22979

UniProt: Q9Y2G0