EXOSC4 anticorps (AA 51-150) (Biotin)

N° du produit ABIN6943360

Détail du produit anti-EXOSC4 anticorps (Biotin)

Antigène: EXOSC4 (Exosome Component 4 (EXOSC4))

Épitope: AA 51-150

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EXOSC4 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EXOSC4

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur EXOSC4

Antigène: EXOSC4 (Exosome Component 4 (EXOSC4))

Autre désignation: EXOSC4 (EXOSC4 Produits)

Synonymes: anticorps EXOSC4, anticorps zgc:73175, anticorps RRP41, anticorps RRP41A, anticorps Rrp41p, anticorps SKI6, anticorps Ski6p, anticorps hRrp41p, anticorps p12A, anticorps 1110039I09Rik, anticorps 1500001N04Rik, anticorps Rrp41, anticorps exosome component 4, anticorps exosome component 4 S homeolog, anticorps exosc4, anticorps EXOSC4, anticorps CC1G_03561, anticorps exosc4.S, anticorps Exosc4

Sujet:

Synonyms: EXOSC 4, Exosome complex component RRP41, Exosome complex exonuclease RRP41, Exosome component 4, Exosome component Rrp41, FLJ20591, hRrp41p, p12A, EXOS4_HUMAN, Ribosomal RNA processing protein 41, RRP 41, RRP41, RRP41A, Rrp41p, SKI 6, SKI6, Ski6p.

Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3 to 5 exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3 region. EXOSC4 (exosome component 4), also known as SKI6, RRP41 or p12A, is a 245 amino acid protein that localizes to both the nucleus and the cytoplasm and shares 96 % sequence identity with its mouse counterpart. Functioning as a component of the exosome complex, EXOSC4 exhibits 3'-5' exonuclease activity and is required for the 3'-processing of 7S pre-RNA to mature 5.8S rRNA. The gene encoding EXOSC4 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.

ID gène: 54512

UniProt: Q9NPD3