EXOSC5 anticorps (AA 141-235) (AbBy Fluor® 647)
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- Antigène Voir toutes EXOSC5 Anticorps
- EXOSC5 (Exosome Component 5 (EXOSC5))
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Épitope
- AA 141-235
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EXOSC5 est conjugé à/à la AbBy Fluor® 647
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat,Dog,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human EXOSC5
- Isotype
- IgG
- Top Product
- Discover our top product EXOSC5 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- EXOSC5 (Exosome Component 5 (EXOSC5))
- Autre désignation
- EXOSC5 (EXOSC5 Produits)
- Synonymes
- anticorps si:ch211-194n6.2, anticorps zgc:153707, anticorps EXOSC5, anticorps RRP41B, anticorps RRP46, anticorps Rrp46p, anticorps hRrp46p, anticorps p12B, anticorps D7Wsu180e, anticorps exosome component 5, anticorps exosc5, anticorps EXOSC5, anticorps Exosc5
- Sujet
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Synonyms: Chronic myelogenous leukemia tumor antigen 28, CML28, EXOS5_HUMAN, EXOSC 5, Exosc5, Exosome complex component rrp46, exosome complex exonuclease RRP46, Exosome component 5, exosome component Rrp46, hRrp46p, p12B, Ribosomal RNA processing protein 46, Ribosomal RNA processing protein 46, S. cerevisiae, homolog of, Ribosomal RNA-processing protein 46, RRP41B, RRP46, Rrp46p.
Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3 to 5 exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3 region. EXOSC5 (Exosome component 5), also known as Exosome complex exonuclease RRP46 and CML28 (Chronic myelogenous leukemia tumor antigen 28), is one of at least eleven components of the exosome complex and is required for processing of 7S pre-RNA to mature 5.8S rRNA. Located in the nucleus, EXOSC5 interacts with both EXOSC1 and EXOSC7. EXOSC5 is exclusively expressed in normal testis, though is found to be highly expressed in many hematopoietic and epithelial tumor cell lines, suggesting that it may be an appropriate target for antigen-specific immunotherapy.
- ID gène
- 56915
- UniProt
- Q9NQT4
- Pathways
- SARS-CoV-2 Protein Interactome
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