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EXOSC5 anticorps (AA 141-235) (AbBy Fluor® 750)

EXOSC5 Reactivité: Souris IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 750
N° du produit ABIN6943382
  • Antigène Voir toutes EXOSC5 Anticorps
    EXOSC5 (Exosome Component 5 (EXOSC5))
    Épitope
    • 14
    • 9
    • 2
    • 1
    • 1
    • 1
    AA 141-235
    Reactivité
    • 17
    • 17
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 26
    • 5
    Lapin
    Clonalité
    • 28
    • 3
    Polyclonal
    Conjugué
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EXOSC5 est conjugé à/à la AbBy Fluor® 750
    Application
    • 12
    • 12
    • 12
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EXOSC5
    Isotype
    IgG
    Top Product
    Discover our top product EXOSC5 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    EXOSC5 (Exosome Component 5 (EXOSC5))
    Autre désignation
    EXOSC5 (EXOSC5 Produits)
    Synonymes
    anticorps si:ch211-194n6.2, anticorps zgc:153707, anticorps EXOSC5, anticorps RRP41B, anticorps RRP46, anticorps Rrp46p, anticorps hRrp46p, anticorps p12B, anticorps D7Wsu180e, anticorps exosome component 5, anticorps exosc5, anticorps EXOSC5, anticorps Exosc5
    Sujet

    Synonyms: Chronic myelogenous leukemia tumor antigen 28, CML28, EXOS5_HUMAN, EXOSC 5, Exosc5, Exosome complex component rrp46, exosome complex exonuclease RRP46, Exosome component 5, exosome component Rrp46, hRrp46p, p12B, Ribosomal RNA processing protein 46, Ribosomal RNA processing protein 46, S. cerevisiae, homolog of, Ribosomal RNA-processing protein 46, RRP41B, RRP46, Rrp46p.

    Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3 to 5 exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3 region. EXOSC5 (Exosome component 5), also known as Exosome complex exonuclease RRP46 and CML28 (Chronic myelogenous leukemia tumor antigen 28), is one of at least eleven components of the exosome complex and is required for processing of 7S pre-RNA to mature 5.8S rRNA. Located in the nucleus, EXOSC5 interacts with both EXOSC1 and EXOSC7. EXOSC5 is exclusively expressed in normal testis, though is found to be highly expressed in many hematopoietic and epithelial tumor cell lines, suggesting that it may be an appropriate target for antigen-specific immunotherapy.

    ID gène
    56915
    UniProt
    Q9NQT4
    Pathways
    SARS-CoV-2 Protein Interactome
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