KCTD17 anticorps (AA 1-100) (Biotin)

N° du produit ABIN6943867

Détail du produit anti-KCTD17 anticorps (Biotin)

Antigène: KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))

Épitope: AA 1-100

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCTD17 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris, Rat

Homologie: Human,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KCTD17

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur KCTD17

Antigène: KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))

Autre désignation: KCTD17 (KCTD17 Produits)

Synonymes: anticorps N28155, anticorps AA414907, anticorps AW742389, anticorps 2900008M13Rik, anticorps RGD1311154, anticorps potassium channel tetramerization domain containing 17, anticorps potassium channel tetramerisation domain containing 17, anticorps KCTD17, anticorps Kctd17

Sujet:

Synonyms: BTB, BTB/POZ domain-containing protein KCTD17, FLJ12242, FLJ98761, KCD17_HUMAN, KCTD17, Potassium channel tetramerisation domain containing 17, POZ domain-containing protein KCTD17, RP5-1170K4.4.

Background: Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).

ID gène: 79734

UniProt: Q8N5Z5