KREMEN2 anticorps (AA 351-450) (Biotin)

N° du produit ABIN6943891

Détail du produit anti-KREMEN2 anticorps (Biotin)

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Épitope: AA 351-450

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KREMEN2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KREMEN2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur KREMEN2

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Autre désignation: KREMEN2 (KREMEN2 Produits)

Synonymes: anticorps krm2, anticorps KREMEN2, anticorps MGC147633, anticorps KRM2, anticorps 2900054E04Rik, anticorps Krm2, anticorps kringle containing transmembrane protein 2 S homeolog, anticorps kringle containing transmembrane protein 2, anticorps kremen2.S, anticorps KREMEN2, anticorps kremen2, anticorps Kremen2

Sujet:

Synonyms: Dickkopf receptor 2, KREM2_HUMAN, KREMEN 2, Kremen protein 2, Kremen protein 2 precursor, Kremen2, Kringle containing protein marking the eye and the nose, Kringle containing transmembrane protein 2, Kringle domain containing transmembrane protein 2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose, KRM 2, KRM2, MGC10791, MGC16709.

Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

ID gène: 79412

UniProt: Q8NCW0

Pathways: Signalisation WNT