METAP2 anticorps

N° du produit ABIN6944076

Détail du produit anti-METAP2 anticorps

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp METAP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant protein within C-terminal human Methionine Aminopeptidase 2.

Clone: 2G3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur METAP2

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Autre désignation: METAP2 (METAP2 Produits)

Synonymes: anticorps metap2, anticorps MGC53792, anticorps METAP2, anticorps GB13458, anticorps DDBDRAFT_0190923, anticorps DDBDRAFT_0304991, anticorps DDB_0190923, anticorps DDB_0304991, anticorps 4930584B20Rik, anticorps A930035J23Rik, anticorps AI047573, anticorps AL024412, anticorps AU014659, anticorps Amp2, anticorps Mnpep, anticorps p67, anticorps p67eIF2, anticorps MAP2, anticorps MNPEP, anticorps wu:fb98h06, anticorps zgc:66250, anticorps methionyl aminopeptidase 2 L homeolog, anticorps methionyl aminopeptidase 2, anticorps methionine aminopeptidase 2, anticorps methionine aminopeptidase, anticorps methionyl aminopeptidase 2 S homeolog, anticorps methionyl aminopeptidase 2b, anticorps metap2.L, anticorps METAP2, anticorps metap2, anticorps LOC551771, anticorps CAALFM_C604080WA, anticorps Metap2, anticorps metap2.S, anticorps metap2b

Sujet:

Synonyms: Methionine aminopeptidase 2, Initiation factor 2-associated 67 kDa glycoprotein, Peptidase M, MetAP 2, p67, p67eIF2, METAP2, MNPEP, P67EIF2

Background: Methionine aminopeptidases (MetAP), also designated peptidase M proteins, are members of the M24 family of proteins. Both MetAP-1 and MetAP-2 release N-terminal amino acids, usually methionine, from nascent peptides and arylamines. Eukaryotes contain both MetAP-1 and MetAP-2, whereas prokaryotes possess only the MetAP-1 enzyme. MetAP-1 and MetAP-2 control cell proliferation in mammalian cells. MetAP-2 is highly conserved between human and Saccharomyces cerevisiae. Neurofibromin (NF1) regulates MetAp-2 and increased expression of MetAP-2 correlates with several forms of cancer. Inhibitors of MetAP-2 are potential targets in cancer therapeutics, particularly in NF1-associated tumor proliferation. Chemotherapeutic drugs such as ovalicin and fumagillin bind to the active site of and inhibit MetAp-2.

ID gène: 10988

UniProt: P50579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling