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PKC iota anticorps (AA 181-280) (Biotin)

PRKCI Reactivité: Humain, Souris WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN6944559
  • Antigène Voir toutes PKC iota (PRKCI) Anticorps
    PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
    Épitope
    • 14
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 181-280
    Reactivité
    • 42
    • 35
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 36
    • 6
    Lapin
    Clonalité
    • 36
    • 6
    Polyclonal
    Conjugué
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PKC iota est conjugé à/à la Biotin
    Application
    • 34
    • 14
    • 13
    • 13
    • 11
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PKC iota/PKCI
    Isotype
    IgG
    Top Product
    Discover our top product PRKCI Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
    Autre désignation
    PKC iota (PRKCI Produits)
    Synonymes
    anticorps DXS1179E, anticorps PKCI, anticorps nPKC-iota, anticorps aPKC[l], anticorps hal, anticorps has, anticorps PRKCI, anticorps PKC, anticorps 2310021H13Rik, anticorps AI427505, anticorps PKClambda, anticorps Pkci, anticorps Pkcl, anticorps Prkcl, anticorps aPKClambda, anticorps mKIAA4165, anticorps protein kinase C iota, anticorps protein kinase C, iota, anticorps PRKCI, anticorps prkci, anticorps Prkci
    Sujet

    Synonyms: aPKC lambda/iota, aPKC-lambda/iota, Atypical protein kinase C lambda/iota, Atypical protein kinase C-lambda/iota, DXS1179E, KPCI_HUMAN, MGC26534, nPKC iota, nPKC-iota, nPKCiota, PKC lambda, PKCI, PKCiota, PKClambda, PRKC iota, PRKC lambda/iota, PRKC-lambda/iota, PRKCI, Protein kinase C iota, Protein kinase C iota type.

    Background: This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]

    ID gène
    5584
    UniProt
    P41743
    Pathways
    Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
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