SPCS2 anticorps (AA 2-100) (Biotin)

N° du produit ABIN6945028

Détail du produit anti-SPCS2 anticorps (Biotin)

Antigène: SPCS2 (Signal Peptidase Complex Subunit 2 Homolog (SPCS2))

Épitope: AA 2-100

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPCS2 est conjugé à/à la Biotin

Application: ELISA, Western Blotting (WB)

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SPCS2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur SPCS2

Antigène: SPCS2 (Signal Peptidase Complex Subunit 2 Homolog (SPCS2))

Autre désignation: SPCS2 (SPCS2 Produits)

Synonymes: anticorps RGD1311253, anticorps 5730406I15Rik, anticorps AA408713, anticorps mKIAA0102, anticorps SPC25, anticorps signal peptidase complex subunit 2, anticorps signal peptidase complex subunit 2 homolog (S. cerevisiae), anticorps Spcs2, anticorps SPCS2

Sujet:

Synonyms: Microsomal signal peptidase 25 kDa subunit, Signal peptidase complex subunit 2, Signal peptidase complex subunit 2 homolog (S. cerevisiae), SPase 25 kDa subunit, SPCS2, SPCS2_HUMAN.

Background: SPCS2 is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

ID gène: 9789

UniProt: Q15005

Pathways: Peptide Hormone Metabolism