Tropomyosin anticorps

N° du produit ABIN6945226

Détail du produit anti-Tropomyosin anticorps

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Tropomyosin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant protein within human Tropomyosin 1 aa 100-300.

Clone: 2G2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Tropomyosin

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Autre désignation: Tropomyosin 1 (TPM1 Produits)

Synonymes: anticorps alpha-fTM, anticorps Tm7, anticorps tpm1, anticorps MGC84844, anticorps AA986836, anticorps AI854628, anticorps TM2, anticorps Tm3, anticorps Tmpa, anticorps Tpm-1, anticorps alpha-TM, anticorps Alpha-tm, anticorps Tma2, anticorps Tmsa, anticorps TPM1, anticorps fb37a09, anticorps tm, anticorps wu:fb37a09, anticorps CH1, anticorps alpha-tm, anticorps alpha-tropomyosin, anticorps C15orf13, anticorps CMD1Y, anticorps CMH3, anticorps HTM-alpha, anticorps TMSA, anticorps TPMA, anticorps Tm1, anticorps zgc:171719, anticorps zgc:55951, anticorps zgc:77009, anticorps tropomyosin 1 (alpha), anticorps tropomyosin, anticorps tropomyosin 1, anticorps tropomyosin 1, alpha, anticorps alpha-tropomyosin, anticorps tropomyosin 1 L homeolog, anticorps TPM1, anticorps tm7, anticorps Tpm1, anticorps tpma, anticorps tpm1.L, anticorps Smp_044010.2, anticorps LOC732984, anticorps tpm1

Sujet:

Synonyms: Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1, TPM1, C15orf13, TMSA

Background: Tropomyosins are a group of structural proteins. Tropomyosins are present in virtually all eukaryotic cells, both muscle and non-muscle, where they bind Actin filaments and function to modulate Actin-Myosin interaction and stabilize Actin filament structure. Tropomyosin _ is encoded by the TPM1 gene, which maps to human chromosome 15q22.1 and undergoes alternative splicing to generate at least four isoforms, including skeletal muscle (isoform 1), smooth muscle (isoform 2), fibroblast/TM3 (isoform 3) and isoform 4. Troponin I binds Tropomyosin at a specific region and the association of Tropomyosin-Troponin with Actin filaments may increase the rigidity of Actin filaments. Tropomyosin also interacts with Caldesmon to regulate smooth muscle contraction.

ID gène: 7168

UniProt: P09493

Pathways: Regulation of Actin Filament Polymerization