USP14 anticorps

N° du produit ABIN6945262

Détail du produit anti-USP14 anticorps

Antigène: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp USP14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Humain, Souris, Rat, Poisson zèbre (Danio rerio)

Purification: Purified by Protein A.

Immunogène: Recombinant protein within human USP14 aa 300 to the C-terminus

Clone: 4C7

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 12 months

Détails sur USP14

Antigène: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Autre désignation: Usp14 (USP14 Produits)

Synonymes: anticorps TGT, anticorps DDBDRAFT_0202821, anticorps DDBDRAFT_0237695, anticorps DDB_0202821, anticorps DDB_0237695, anticorps 2610005K12Rik, anticorps 2610037B11Rik, anticorps AW107924, anticorps C78769, anticorps ax, anticorps zgc:55949, anticorps wu:fk63d09, anticorps MGC81945, anticorps tgt, anticorps MGC69343, anticorps USP14, anticorps ubiquitin specific peptidase 14, anticorps peptidase C19 family protein, anticorps ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase), anticorps ubiquitin specific protease 14, anticorps ubiquitin specific peptidase 14 S homeolog, anticorps universal stress protein, anticorps Ubiquitin carboxyl-terminal hydrolase 14, anticorps USP14, anticorps usp14, anticorps Usp14, anticorps Bm1_28765, anticorps usp14.S, anticorps RR_RS06480, anticorps usp-14

Sujet:

Synonyms: Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14, USP14, TGT.

Background: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

ID gène: 9097

UniProt: P54578