Histone 3 anticorps (H3K27me3)
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- Antigène Voir toutes Histone 3 (H3) Anticorps
- Histone 3 (H3)
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Épitope
- H3K27me3
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Histone 3 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), ELISA, Chromatin Immunoprecipitation (ChIP), Dot Blot (DB), ChIP DNA-Sequencing (ChIP-seq), Cleavage Under Targets and Tagmentation (CUT&Tag)
- Specificité
- Polyclonal antibody raised in rabbit against against histone H3, trimethylated at lysine 27 (H3K27me3), using a KLH-conjugated synthetic peptide.
- Réactivité croisée
- Arabidopsis, Boeuf (Vache), Mouche des fruits (Drosophila melanogaster), Souris, Porc, Rat (Rattus), Schistosoma japonicum, Poisson zèbre (Danio rerio)
- Purification
- Peptide affinity purified
- Classe de qualité
- ChIP-seq Grade
- Immunogène
- synthetic peptide
- Top Product
- Discover our top product H3 Anticorps primaire
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- Indications d'application
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ChIP/ChIP-seq 1 μg:ChIP
ELISA 1:5,000
Dot Blot 1:20,000
WB 1:1,000
IF 1:500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.6 μg/μL
- Buffer
- PBS, 0.05 % azide, 0.05 % ProClin300
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- Histone 3 (H3)
- Autre désignation
- Histone 3 (H3 Produits)
- Synonymes
- anticorps H-3, anticorps histocompatibility 3, anticorps H3
- Sujet
- Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called "histone code". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Trimethylation of histone H3K27 is associated with gene repression.
- UniProt
- P68431
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