SARS-CoV-2 Spike S1 anticorps (RBD)

N° du produit ABIN6952746

Détail du produit anti-SARS-CoV-2 Spike S1 anticorps

Antigène: SARS-CoV-2 Spike S1

Épitope: RBD

Reactivité: SARS Coronavirus-2 (SARS-CoV-2)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SARS-CoV-2 Spike S1 est non-conjugé

Application: ELISA

Fonction: Polyclonal Rabbit antibody against SARS-CoV-2 (COVID-19) Spike Protein S1 Receptor Binding Domain

Specificité: This antibody was selected for its ability to bind to the virus SARS-CoV-2 Spike Protein Receptor Binding Domain (RBD) from the disease COVID-19.

Attributs du produit: Rabbit anti-SARS-CoV-2 S1 RBD antibody

Purification: The IgG fraction was purified by Protein A affinity chromatography.

Immunogène: This antibody was produced from antiserum of rabbits immunized with a recombinant SARS-CoV-2 S1 RBD protein.

Isotype: IgG

Information d'application

Indications d'application: ELISA (recommended work dilution = 1:160,000)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute the antibody with sterile water to a final concentration of 1 mg/mL.

Buffer: Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution.

Conseil sur la manipulation: Please avoid freeze-thaw cycles, as this will lower the activity of the antibody.

Stock: -20 °C

Stockage commentaire: Store at 4°C if intended for use within one month, otherwise, store at -20°C to -80°C. The lyophilized antibody is stable for at least 18 months after the date of receipt when stored at -20°C to -80°C. After reconstitution, it can be aliquoted and stored frozen at -20°C to -80°C in a manual defrost freezer for at least 6 months without detectable loss of activity. Upon reconstitution, the antibody can also be stored for 1 month at 4°C.

Références pour anticorps anti-SARS-CoV-2 Spike S1 (ABIN6952746)

Azad, Singaravelu, Taha, Jamieson, Boulton, Crupi, Martin, Brown, Poutou, Ghahremani, Pelin, Nouri, Rezaei, Marshall, Enomoto, Arulanandam, Alluqmani, Samson, Gingras, Cameron, Greer, Ilkow, Diallo et al.: "Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry. ..." dans: Molecular therapy : the journal of the American Society of Gene Therapy, (2021) (PubMed).

Détails sur SARS-CoV-2 Spike S1

Antigène: SARS-CoV-2 Spike S1

Abstract: SARS-CoV-2 Spike S1 Produits

Synonymes: anticorps E2, anticorps Surface Glycoprotein, anticorps S

Classe de substances: Viral Protein

Sujet: It's been reported that 2019-nCoV (COVID-19) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

ID gène: 43740568

UniProt: P0DTC2