KLRG1 anticorps (FITC)
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- Antigène Voir toutes KLRG1 Anticorps
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
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Reactivité
- Souris
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Hôte
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Golden Syrian Hamster
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp KLRG1 est conjugé à/à la FITC
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Application
- Flow Cytometry (FACS)
- Purification
- This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
- Clone
- 2F1
- Isotype
- IgG
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- Indications d'application
- This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indi- cated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.
- Commentaires
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0.5 mg/mL
- Restrictions
- For Research Use only
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- Buffer
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- 2-8°C protected from light
- Date de péremption
- 12 months
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- Antigène
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
- Autre désignation
- KLRG1 (KLRG1 Produits)
- Synonymes
- anticorps KLRG1, anticorps 2F1-Ag, anticorps MAFA, anticorps MAFA-L, anticorps 2F1, anticorps CLEC15A, anticorps MAFA-2F1, anticorps MAFA-LIKE, anticorps killer cell lectin like receptor G1, anticorps killer cell lectin-like receptor subfamily G, member 1, anticorps KLRG1, anticorps Klrg1
- Sujet
- The 2F1 antibody reacts with mouse KLRG1 (Killer cell Lectin-like Receptor G1). This 30-38 kDa homodimeric receptor may be expressed by activated, mature NK cells and by effector/memory T cells, with potentially different roles in each cell type. KLRG1 can regulate, in an inhibitory fashion, the development and effector functions of NK cells, and is often cited as a senescence or terminal differentiation marker for T cells. Ligands for KLRG1 include members of the cadherin family of adhesion molecules, specifically N-Cadherin, E-Cadherin, and R-Cadherin. These interactions may induce bidirectional, immunosuppressive signaling in both KLRG- and Cadherin-expressing cells. A more recently identified role for KLRG1-Cadherin signaling in tissue organization, e.g. in cardiac angiogenesis, expands the function of these interactions beyond immunosuppression of immune cells. (Bouchentouf et al. 2010. J. Immunol. 185: 7014-7025). The 2F1 antibody may be used as a phenotypic marker for KLRG1 in mouse, frequently in combination with Anti-Mouse CD127 antibody (clone A7R34), for identification of effector T cell populations.
- ID gène
- 50928
- UniProt
- O88713
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