IL-21 anticorps (Biotin)

N° du produit ABIN6963916

Détail du produit anti-IL-21 anticorps (Biotin)

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-21 est conjugé à/à la Biotin

Application: ELISA, ELISpot

Specificité: Native and recombinant human IL-21

Réactivité croisée (Details): The monoclonal antibody cross-reacts with IL-21 from non-human primates. See the Human/NHP cross-reactivity table.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogène: Recombinant human IL-21

Clone: MT21-3m

Isotype: IgG1

Information d'application

Indications d'application: For quantification of IL-21 in solution e.g. cell culture supernatants using ELISA and for enumeration of IL-21 producing cells using ELISpot. MT21.3m is recommended as detection mAb in combination with coating mAb MT216G . The antibody is also suitable for Western blot.

Commentaires:

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Date de péremption: 18 months

Références pour anticorps anti-IL-21 (Biotin) (ABIN6963916)

Yamamoto, Kitawaki, Sugimoto, Fujita, Kawase, Takaori-Kondo, Kadowaki: "Anti-inflammatory modulation of human myeloid-derived dendritic cell subsets by lenalidomide." dans: Immunology letters, Vol. 211, pp. 41-48, (2020) (PubMed).

Amu, Lantto Graham, Bekele, Nasi, Bengtsson, Rethi, Sorial, Meini, Zazzi, Hejdeman, Chiodi: "Dysfunctional phenotypes of CD4+ and CD8+ T cells are comparable in patients initiating ART during early or chronic HIV-1 infection." dans: Medicine, Vol. 95, Issue 23, pp. e3738, (2017) (PubMed).

Li, Sullivan, Rouphael, Yu, Banton, Maddur, McCausland, Chiu, Canniff, Dubey, Liu, Tran, Hagan, Duraisingham, Wieland, Mehta, Whitaker, Subramaniam, Jones, Sette, Vora, Weinberg, Mulligan, Nakaya et al.: "Metabolic Phenotypes of Response to Vaccination in Humans. ..." dans: Cell, Vol. 169, Issue 5, pp. 862-877.e17, (2017) (PubMed).

Huang, Ehrnfelt, Paulie, Zuber, Ahlborg: "ELISpot and ELISA analyses of human IL-21-secreting cells: Impact of blocking IL-21 interaction with cellular receptors." dans: Journal of immunological methods, Vol. 417, pp. 60-66, (2015) (PubMed).

Détails sur IL-21

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Autre désignation: IL21 (IL21 Produits)

Synonymes: anticorps IL-21, anticorps Za11, anticorps interleukin 21, anticorps IL21, anticorps Il21

ID gène: 59067

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response