IL23 anticorps

N° du produit ABIN6964023

Détail du produit anti-IL23 anticorps

Antigène: IL23 (Interleukin 23 (IL23))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL23 est non-conjugé

Application: Neutralization (Neut)

Specificité: Native and recombinant IL-23. The antibody recognizes the p19 subunit of the IL-23 heterodimer (p40+p19).

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogène: Recombinant human IL-23

Clone: MT155

Isotype: IgG2b

Information d'application

Indications d'application: Neutralization of human IL-23 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays. Neutralization Neutralization assay: Neutralization of human IL-23 induced IFN-γ production (see graph). To determine the neutralizing capacity and ND50, mixtures of various concentrations of mAb MT155, human recombinant IL-23 (10 ng/mL) and recombinant human IL-18 (50 ng/mL) were added to human PBMC. Following overnight incubation, cell supernatants were quantified in IFN-γ ELISA. Neutralization dose 50 (ND50): MT155 neutralized the effect of IL-23 at a ND50value of 0.2-0.8 μg/mL when 10 ng/mL recombinant human IL-23 was present. ND50 is defined as the concentration of antibody that results in 50 % inhibition of the biological response under the experimental conditions specified.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.

Date de péremption: 18 months

Détails sur IL23

Antigène: IL23 (Interleukin 23 (IL23))

Autre désignation: IL23 (IL23 Produits)

Synonymes: anticorps IL-23, anticorps p19, anticorps SGRF, anticorps il23p19, anticorps interleukin 23, alpha subunit p19, anticorps interleukin 23 subunit alpha, anticorps Il23a, anticorps IL23A

ID gène: 51561