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5-Methylcytosine anticorps

Reactivité: Humain MeDIP, IF, DB Hôte: Souris Monoclonal A1 unconjugated
N° du produit ABIN6971343
  • Antigène
    5-Methylcytosine
    Reactivité
    Humain
    Hôte
    • 22
    • 8
    • 3
    Souris
    Clonalité
    • 24
    • 9
    Monoclonal
    Conjugué
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Inconjugué
    Application
    • 20
    • 16
    • 13
    • 9
    • 8
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Methylated DNA Immunoprecipitation (MeDIP), Immunofluorescence (IF), Dot Blot (DB)
    Attributs du produit
    5-Methylcytosine (5-mC) is a modified base that is found in the DNA of plants and vertebrates. DNA methylation is an epigenetic event in which DNA methyltransferases (DNMTs) catalyze the reaction of a methyl group to the fifth carbon of cytosine in a CpG dinucleotide. This modification helps to control gene expression and is also involved in genomic imprinting, while aberrant DNA methylation is often associated with disease. The 5-methylcytidine antibody (Clone A1) has been developed to discriminate between the modified base and its normal cytosine counterpart, allowing for gene promoter methylation analysis. 5-Methylcytosine (5-mC) antibody (mAb) (Clone A1) was raised in a Mouse host. It has been validated for use in Dot blot, Immunofluorescence and Methyl DNA Immunoprecipitation, it has been shown to react with Human samples, but the sequence is not species specific so it should react with a wide range of sample types.
    Purification
    Protein A Chromatography
    Immunogène
    This 5-Methylcytosine (5-mC) antibody was raised against 5-Methyl-cytidine conjugated to KLH and recognizes 5-Methylcytosine.
    Clone
    A1
    Isotype
    IgG1
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Antigène
    5-Methylcytosine
    Autre désignation
    5-Methylcytosine (5-mC)
    Classe de substances
    Chemical
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