AGO4 anticorps (N-Term)

N° du produit ABIN6971369

Détail du produit anti-AGO4 anticorps

Antigène: AGO4 (EIF2C4) (Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGO4 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Argonaute 4 (Ago4, aka EIF2C4) is a member of the Argonaute family of proteins involved in RNAi mediated gene silencing through siRNA and miRNA effectors. The Argonaute proteins are part of RISC, the RNAi Induced Silencing Complex. Ago4 lacks RNase activity and does not appear to cleave target mRNA molecules. It binds to microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Ago4 has both a PAZ and a PIWI domain, indicative of the Argonaute family of proteins. Ago4 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This Ago4 antibody was raised against a peptide within the N-terminal region of human Ago4.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur AGO4

Antigène: AGO4 (EIF2C4) (Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4))

Autre désignation: Ago4 (EIF2C4 Produits)

Synonymes: anticorps EIF2C4, anticorps ago4, anticorps Argonaute4, anticorps argonaute-4, anticorps eif2c4, anticorps wu:fd14f04, anticorps ARGONAUTE 4, anticorps OCP11, anticorps OVEREXPRESSOR OF CATIONIC PEROXIDASE 11, anticorps T20P8.9, anticorps T20P8_9, anticorps Eif2c4, anticorps 5730550L01Rik, anticorps AI481660, anticorps argonaute 4, RISC catalytic component, anticorps argonaute 1, RISC catalytic component, anticorps argonaute RISC catalytic component 4, anticorps Argonaute family protein, anticorps argonaute 4, RISC catalytic component L homeolog, anticorps argonaute RISC catalytic subunit 4, anticorps AGO4, anticorps ago1, anticorps ago4, anticorps Ago4, anticorps ago4.L

Poids moléculaire: 100 kDa

NCBI Accession: NP_060099

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process