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Cullin 4B anticorps (N-Term)

CUL4B Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6971562
  • Antigène Voir toutes Cullin 4B (CUL4B) Anticorps
    Cullin 4B (CUL4B)
    Épitope
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 60
    • 22
    • 21
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 55
    • 5
    Lapin
    Clonalité
    • 57
    • 3
    Polyclonal
    Conjugué
    • 32
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Cullin 4B est non-conjugé
    Application
    • 40
    • 19
    • 9
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Attributs du produit
    CUL4B (Cullin 4B) is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, Histone H2A, Histone H3 and Histone H4 in response to radiation-induced DNA damage and may act as a transcriptional corepressor by ubiquitination of Histone H2AK119 and recruiting PRC2 complexes. CUL4B antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
    Purification
    Affinity Purified
    Immunogène
    This antibody was raised against a peptide within the N-terminal region of human CUL4B.
    Isotype
    IgG
    Top Product
    Discover our top product CUL4B Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Antigène
    Cullin 4B (CUL4B)
    Autre désignation
    CUL4B (CUL4B Produits)
    Synonymes
    anticorps MRXHF2, anticorps MRXS15, anticorps MRXSC, anticorps SFM2, anticorps 2700050M05Rik, anticorps AA409770, anticorps CUL-4B, anticorps mKIAA0695, anticorps RGD1564494, anticorps im:7140950, anticorps im:7150765, anticorps MGC115611, anticorps Tb03.1J15.620, anticorps sfm2, anticorps mrxsc, anticorps mrxhf2, anticorps cullin 4B, anticorps cullin 4B S homeolog, anticorps CUL4B, anticorps Cul4b, anticorps cul4b, anticorps cul4b.S, anticorps Tb927.3.1290
    Poids moléculaire
    110 kDa
    NCBI Accession
    NP_003579
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