GLYR1 anticorps (C-Term)

N° du produit ABIN6971688

Détail du produit anti-GLYR1 anticorps

Antigène: GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLYR1 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: GLYR1 / NDF (nucleosome-destabilizing factor) that is recruited to gene bodies during transcriptional activation and facilitates Pol II transcription through nucleosomes, where it is proposed to ""unzip"" chromatin during transcription, pushing the polymerase past pause points. It was discovered as a factor that allows p300 to acetylate Histone H3K56, which is normally an inaccessible residue for this modification. GLYR1 is shown to associate with a subset of highly transcribed genes tending to have longer mRNAs rather than shorter, and is also at a significant subset of loci containing the Histone H3K36me3. GLYR1 is expressed at high levels in most tissue types, including stem cells, and has been found to be overexpressed in breast cancer. GLYR1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This antibody was raised against a peptide within the C-terminal region of human GLYR1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris, 105 mM NaCl, 0.07 mM EDTA, 31 mM glycine, 30 % glycerol, and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur GLYR1

Antigène: GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))

Autre désignation: GLYR1 (GLYR1 Produits)

Synonymes: anticorps N-PAC, anticorps BM045, anticorps HIBDL, anticorps NP60, anticorps 2810419J22Rik, anticorps 3930401K13Rik, anticorps AW545332, anticorps Npac, anticorps 3930401k13rik, anticorps N-pac, anticorps RGD1309459, anticorps glyoxylate reductase 1 homolog, anticorps glyoxylate reductase 1 homolog (Arabidopsis), anticorps GLYR1, anticorps Glyr1

Poids moléculaire: 65 kDa

NCBI Accession: NP_115958