HIRA anticorps (AA 421-729)

N° du produit ABIN6971735

Détail du produit anti-HIRA anticorps

Antigène: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Épitope: AA 421-729

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HIRA est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Attributs du produit: HIRA (DGCR1, TUP1) is a histone chaperone that preferentially places the variant Histone H3.3 in nucleosomes, replacing canonical Histone H3 during the cell cycle. HIRA is required for the periodic repression of histone gene transcription during the cell cycle and when complexed with ASF1a is involved in the formation of the senescence-associated heterochromatin foci. HIRA antibody (mAb) (Clone WC15) was raised in a Mouse host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human and Mouse samples.

Purification: Protein G Chromatography

Immunogène: This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.

Clone: WC15

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur HIRA

Antigène: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Autre désignation: HIRA (HIRA Produits)

Synonymes: anticorps HIRA, anticorps wu:fb97b07, anticorps wu:fi43b08, anticorps si:ch211-188g24.3, anticorps AA138857, anticorps D16Ertd95e, anticorps N28177, anticorps Tuple1, anticorps DGCR1, anticorps TUP1, anticorps TUPLE1, anticorps dgcr1, anticorps hira-A, anticorps tup1, anticorps tuple1, anticorps homolog of histone chaperone HIRA, anticorps histone cell cycle regulator, anticorps histone cell cycle regulator a, anticorps protein HIRA, anticorps HIR histone cell cycle regulation defective homolog A (S. cerevisiae), anticorps HIRA, anticorps histone cell cycle regulator S homeolog, anticorps histone chaperone HIRA-like protein, anticorps Tuple1/HirA, anticorps HIRA, anticorps hira, anticorps LOC100052845, anticorps LOC100352472, anticorps LOC100407742, anticorps LOC100450459, anticorps LOC100467668, anticorps LOC100581135, anticorps LOC486424, anticorps Hira, anticorps LOC732736, anticorps hira.S

Poids moléculaire: 120 kDa

NCBI Accession: NP_003316

Pathways: Chromatin Binding