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MBD1 anticorps (C-Term)

MBD1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6972316
  • Antigène Voir toutes MBD1 Anticorps
    MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
    Épitope
    • 15
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 40
    • 19
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 31
    • 9
    Lapin
    Clonalité
    • 33
    • 7
    Polyclonal
    Conjugué
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MBD1 est non-conjugé
    Application
    • 33
    • 13
    • 13
    • 12
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Attributs du produit
    MBD1 (methyl-CpG binding domain protein 1) is thought to function as a mediator of the biological consequences of DNA methylation. Methylation of mammalian DNA has long been recognized to play a major role in a number of cellular functions such as development and control of gene expression. It is generally associated with the repressive chromatin state. The complex series of events leading to this repressive state involve the coordinated regulation of DNA methyltransferases and two other groups of proteins called the Methyl-CpG binding proteins (MBD proteins) and the Kaiso family of proteins. The MBD family of proteins include MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD1 is recruited to both methylated and non-methylated CpGs via separate domains: the CXXC domain targets the protein to non-methylated CpGs whereas the MBD domain targets the protein to methylated CpG. During S phase of the cell cycle, MBD1 can interact with SETDB1 (H3K9 methyltransferase). MBD1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
    Purification
    Affinity Purified
    Immunogène
    This MBD1 antibody was raised against a peptide within the C-terminal region of human MBD1.
    Isotype
    IgG
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    Discover our top product MBD1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Antigène
    MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
    Autre désignation
    MBD1 (MBD1 Produits)
    Synonymes
    anticorps CXXC3, anticorps PCM1, anticorps RFT, anticorps Cxxc3, anticorps CCDC11, anticorps methyl-CpG binding domain protein 1, anticorps MBD1, anticorps Mbd1
    Poids moléculaire
    80 kDa
    NCBI Accession
    NP_056671
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