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N6-Methyladenosine anticorps

Reactivité: Humain, Saccharomyces cerevisiae DB, IP Hôte: Souris Monoclonal 17-3-4-1 unconjugated
N° du produit ABIN6972397
  • Antigène
    N6-Methyladenosine
    Reactivité
    Humain, Saccharomyces cerevisiae
    Hôte
    • 1
    • 1
    Souris
    Clonalité
    • 1
    • 1
    Monoclonal
    Conjugué
    • 2
    Inconjugué
    Application
    Dot Blot (DB), Immunoprecipitation (IP)
    Attributs du produit
    N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3' UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well. N6-Methyladenosine (m6A) antibody (mAb) (Clone 17-3-4-1) was raised in a Mouse host. It has been validated for use in Dot blot and Immunoprecipitation, it has been shown to react with Budding Yeast and Human samples, but the sequence is not species specific so it should react with a wide range of sample types.
    Purification
    Protein A Chromatography
    Immunogène
    This antibody was raised against 6-Methyladenosine conjugated to BSA.
    Clone
    17-3-4-1
    Isotype
    IgG1 kappa
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Antigène
    N6-Methyladenosine
    Autre désignation
    N6-Methyladenosine (m6A)
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