SMC3 anticorps (C-Term)

N° du produit ABIN6972756

Détail du produit anti-SMC3 anticorps

Antigène: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMC3 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: The Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. SMC3 is a component of the cohesin complex that plays an essential role during chromatid segregation. SMC3 is also involved in DNA recombination and repair, mitotic chromosome organization and microtubule-mediated intracellular transport. SMC3 is acetylated during replication, which is essential for cohesion, and is phosphorylated by ATM subsequent to DNA double strand breakage. SMC3 is frequently elevated in human colon carcinoma and overexpression of the protein transforms fibroblasts. SMC3 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This SMC3 antibody was raised against a peptide in the C-terminal region of human SMC3.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur SMC3

Antigène: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Autre désignation: SMC3 (SMC3 Produits)

Synonymes: anticorps cspg6, anticorps xsmc3, anticorps BAM, anticorps BMH, anticorps CDLS3, anticorps CSPG6, anticorps HCAP, anticorps SMC3L1, anticorps Bamacan, anticorps Cspg6, anticorps Mmip1, anticorps SMC-3, anticorps SmcD, anticorps im:7142991, anticorps wu:fb22e01, anticorps wu:fc30d07, anticorps bamacan, anticorps structural maintenance of chromosomes 3, anticorps structural maintenance of chromosomes 3 S homeolog, anticorps smc3, anticorps SMC3, anticorps Smc3, anticorps smc3.S

Poids moléculaire: 150 kDa

NCBI Accession: NP_005436

Pathways: Stem Cell Maintenance