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DBNL anticorps (AA 201-300) (AbBy Fluor® 350)

DBNL Reactivité: Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 350
N° du produit ABIN6976893
  • Antigène Voir toutes DBNL Anticorps
    DBNL (Drebrin-Like (DBNL))
    Épitope
    • 14
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reactivité
    • 25
    • 18
    • 2
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 36
    • 2
    • 1
    Lapin
    Clonalité
    • 37
    • 2
    Polyclonal
    Conjugué
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DBNL est conjugé à/à la AbBy Fluor® 350
    Application
    • 37
    • 18
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris
    Homologie
    Human
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human HIP55
    Isotype
    IgG
    Top Product
    Discover our top product DBNL Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    DBNL (Drebrin-Like (DBNL))
    Autre désignation
    HIP55 (DBNL Produits)
    Synonymes
    anticorps ABP1, anticorps HIP-55, anticorps HIP55, anticorps SH3P7, anticorps Abp1, anticorps mAbp1, anticorps Sh3p7, anticorps abp1, anticorps dbnl-B, anticorps DBNL, anticorps DKFZp459C0939, anticorps drebrin like, anticorps drebrin-like, anticorps drebrin like S homeolog, anticorps drebrin 1, anticorps DBNL, anticorps Dbnl, anticorps dbnl.S, anticorps LOC100148204, anticorps DBN1
    Sujet

    Synonyms: ABP1, Actin-binding protein 1, Cervical mucin associated protein, Cervical mucin-associated protein, Cervical SH3P7, CMAP, Dbnl, DBNL_HUMAN, Drebrin F, drebrin like, Drebrin like protein, Drebrin-F, Drebrin-like protein, HIP 55, HIP-55, HPK1 interacting protein of 55 kDa, HPK1-interacting protein of 55 kDa, SH3 domain containing protein 7, SH3 domain-containing protein 7, SH3P7, Src Homology 3 Domain Containing Protein, src homology 3 domain containing protein HIP

    Background: Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.

    ID gène
    28988
    UniProt
    Q9UJU6
    Pathways
    TCR Signaling, Regulation of Actin Filament Polymerization
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