EEFSEC anticorps (AA 21-120) (AbBy Fluor® 488)
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- Antigène Voir toutes EEFSEC Anticorps
- EEFSEC (Eukaryotic Elongation Factor, Selenocysteine-tRNA-Specific (EEFSEC))
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Épitope
- AA 21-120
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EEFSEC est conjugé à/à la AbBy Fluor® 488
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Cow,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human EEFSEC
- Isotype
- IgG
- Top Product
- Discover our top product EEFSEC Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- EEFSEC (Eukaryotic Elongation Factor, Selenocysteine-tRNA-Specific (EEFSEC))
- Autre désignation
- EEFSEC (EEFSEC Produits)
- Synonymes
- anticorps RGD1560552, anticorps EFSEC, anticorps SELB, anticorps Selb, anticorps sec, anticorps eukaryotic elongation factor, selenocysteine-tRNA-specific, anticorps eukaryotic elongation factor, selenocysteine-tRNA specific, anticorps Eefsec, anticorps EEFSEC
- Sujet
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Synonyms: EFSEC, SELB_HUMAN_ Elongation factor for selenoprotein translation, Elongation factor sec, Eukaryotic elongation factor, selenocysteine tRNA specific, SELB, Selenocysteine specific elongation factor.
Background: EEFSEC is a 596 amino acid protein that localizes to both the nucleus and the cytoplasm and belongs to the GTP-binding elongation factor family. Functioning as a translation factor, SELB binds GTP and GDP and is necessary for the incorporation of selenocysteine into target proteins. The gene encoding SELB maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
- ID gène
- 60678
- UniProt
- P57772
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