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IMPACT anticorps (AA 21-120) (AbBy Fluor® 488)

IMPACT Reactivité: Souris, Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 488
N° du produit ABIN6977475
  • Antigène Voir toutes IMPACT Anticorps
    IMPACT (Impact Homolog (IMPACT))
    Épitope
    • 14
    • 14
    • 7
    • 6
    • 2
    • 1
    AA 21-120
    Reactivité
    • 23
    • 15
    • 15
    Souris, Rat
    Hôte
    • 35
    • 2
    Lapin
    Clonalité
    • 37
    Polyclonal
    Conjugué
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IMPACT est conjugé à/à la AbBy Fluor® 488
    Application
    • 33
    • 20
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Sheep,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human IMPACT
    Isotype
    IgG
    Top Product
    Discover our top product IMPACT Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    IMPACT (Impact Homolog (IMPACT))
    Autre désignation
    IMPACT (IMPACT Produits)
    Synonymes
    anticorps zgc:103672, anticorps Ximpact, anticorps impact-A, anticorps RWDD5, anticorps impact-a, anticorps E430016J11Rik, anticorps impact RWD domain protein, anticorps impact, anticorps impact RWD domain protein L homeolog, anticorps impact, RWD domain protein, anticorps IMPACT, anticorps impact, anticorps EDI_298310, anticorps impact.L, anticorps Impact
    Sujet

    Synonyms: Protein IMPACT, IMPACT, Imprinted and ancient gene protein homolog

    Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity).

    ID gène
    55364
    UniProt
    Q9P2X3
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