ADC anticorps (AA 51-150) (AbBy Fluor® 488)

N° du produit ABIN6977493

Détail du produit anti-ADC anticorps (AbBy Fluor® 488)

Antigène: ADC (Arginine Decarboxylase (ADC))

Épitope: AA 51-150

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADC est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ODCp

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ADC

Antigène: ADC (Arginine Decarboxylase (ADC))

Autre désignation: ODCp (ADC Produits)

Synonymes: anticorps MGC134604, anticorps azi2, anticorps odc2, anticorps odc-p, anticorps odc1l, anticorps xodc2, anticorps ADC, anticorps AZI2, anticorps ODC-p, anticorps ODC1L, anticorps 4933429I20Rik, anticorps AZIN2, anticorps Azi2, anticorps B930082O19, anticorps Odcp, anticorps RGD1564776, anticorps odc1-b, anticorps arginine decarboxylase, anticorps antizyme inhibitor 2, anticorps biosynthetic arginine decarboxylase SpeA, anticorps biosynthetic arginine decarboxylase SpeA (ADC), anticorps pyruvoyl-dependent arginine decarboxylase, anticorps antizyme inhibitor 2 S homeolog, anticorps AZIN2, anticorps azin2, anticorps adc, anticorps speA, anticorps Mrub_2839, anticorps MMAH_RS09440, anticorps Arnit_1968, anticorps Mesil_3114, anticorps Trad_0080, anticorps Spirs_3255, anticorps LOC100233080, anticorps Azin2, anticorps azin2.S

Sujet:

Synonyms: Antizyme inhibitor 2, AZIN2, Arginine decarboxylase, ADC, ARGDC, Ornithine decarboxylase-like protein, ODC-like protein, ornithine decarboxylase paralog, ODC-p, AZIN2, ADC, KIAA1945, ODCP

Background: Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240). Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240). Participates in the morphological integrity of the trans-Golgi network (TGN) and functions as a regulator of intracellular secretory vesicle trafficking (PubMed:20188728).

ID gène: 113451

UniProt: Q96A70